If someone is already taking a benzodiazepine medication such as lorazepam or alprazolam, also taking tramadol can result in sedation, respiratory depression, coma, and even death.
People who are taking serotonergic drugs should use tramadol carefully because of the risk of serotonin syndrome. The following table lists serotonergic drug classes :.
People taking tramadol should report any side effects to their doctor. By discussing the benefits and risks of the medication, a doctor can help a person find the most appropriate medicine at the lowest effective dosage. Anyone having difficulty breathing or experiencing any symptoms of serotonin syndrome must seek immediate medical care. According to a World Health Organization WHO report on tramadol, clinical data in adults suggests that the drug has a low potential for dependence.
People may, however, become dependent on tramadol when taking it for more than a few weeks or months. People with a history of drug misuse are more at risk of developing a dependence on tramadol.
In one case study , a year-old male with no history of substance misuse went to the emergency room to get help for tramadol addiction. His tramadol treatment began about 2 years earlier. He was taking up to mg per day and was unable to stop taking it without experiencing withdrawal symptoms.
Tramadol is an opioid pain medication. It also acts on brain chemicals called serotonin and norepinephrine to relieve moderate to severe pain. Tramadol is not safe for everyone. Children under 12 years old should not take tramadol, and those aged 12—18 should use caution when taking it. Some people may experience mild to severe side effects when taking tramadol. Some drug interactions can occur with tramadol, and the effects can be severe.
Although it has a low potential for dependence, the Drug Enforcement Administration DEA control the distribution of tramadol. Clonazepam and Xanax both belong to a class of drugs called benzodiazepines.
They are quite similar, but people use them them for different reasons…. Valium and Xanax are both benzodiazepines. As sedatives, they have some uses in treating anxiety, but the two can cause slightly different side….
Doctors prescribe benzodiazepines for anxiety, insomnia, and other purposes. Do not use two doses at one time. Your doctor may recommend you get naloxone a medicine to reverse an opioid overdose and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up.
Your caregiver must still get emergency medical help and may need to perform CPR cardiopulmonary resuscitation on you while waiting for help to arrive. Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it. The extended-release tablets and capsules are gradually released into your body over 12 or 24 hours.
Your dose will depend on how severe your pain is, how sensitive you are to the medicine, and other factors. You may need to have your dosage adjusted several times before you and your doctor determine what works best. Health Topics. Health Tools. Tramadol Ultram. Reviewed: December 11, You should not take tramadol if you are allergic to it, or if you have: severe asthma or breathing problems; a stomach or bowel obstruction including paralytic ileus ; if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.
Your seizure risk may be higher if you have ever had: a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.
Tell your doctor if you have ever had: breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt. Side Effects. Side Effects What are the side effects of Tramadol Ultram? Call your doctor at once if you have: noisy breathing, sighing, shallow breathing, breathing that stops during sleep; a slow heart rate or weak pulse; a light-headed feeling, like you might pass out; seizure convulsions ; or low cortisol levels --nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.
Common side effects may include: constipation, nausea, vomiting, stomach pain; dizziness, drowsiness, tiredness; headache; or itching. This can worsen your condition or make it harder for doctors to diagnose or find the cause of problems in your brain. For people with stomach problems: Tramadol can make certain stomach problems worse. It can also make it harder for doctors to diagnose or find the cause of problems.
For people with breathing problems: Tramadol may slow your breathing and cause shallow breathing. Shallow breathing means you take small, short breaths. If you already have a breathing problem, such as asthma, talk with your doctor about whether this drug is safe for you.
For pregnant women: Tramadol is a category C pregnancy drug. That means two things:. This drug should only be used if the potential benefit justifies the potential risk to the fetus. Call your doctor right away if you become pregnant while taking this drug.
For women who are breastfeeding: Tramadol may pass into breast milk and cause serious effects in a child who is breastfed. These effects can include slowed breathing and death. Talk to your doctor if you breastfeed your child. For seniors: The kidneys or liver of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.
Seniors 65 years of age and older are at higher risk of side effects from the extended-release forms of this drug. Tramadol oral tablet is used for short-term or long-term treatment. Your length of treatment depends on how severe your pain is. If you stop taking the drug suddenly, you may have symptoms of withdrawal, which can include:. For this drug to work well, a certain amount needs to be in your body at all times.
If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:. But if your symptoms are severe, call or go to the nearest emergency room right away. What to do if you miss a dose: Take your dose as soon as you remember. If you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects. A prescription for this medication is refillable.
Your doctor will write the number of refills authorized on your prescription. You or your pharmacy may have to contact your doctor for a new prescription if you need this medication refilled. Your doctor should monitor certain health issues.
This can help make sure you stay safe while you take this drug. These issues include:. You may need to have blood tests during your treatment with tramadol. The cost of these tests will depend on your insurance coverage. Tramadol should also not be used in used in children 12 to 18 years of age who are obese or who have a neuromuscular disease disease that affects the nerves that control voluntary muscles , a lung disease, or obstructive sleep apnea condition in which the airway becomes blocked or narrow and breathing stops for short periods during sleep as these conditions may increase their risk of breathing problems.
Taking certain other medications during your treatment with tramadol may increase the risk that you will experience breathing problems or other serious, life threatening breathing problems, sedation, or coma. Tell your doctor if you are taking or plan to take any of the following medications: amiodarone Nexterone, Pacerone ; certain antifungal medications including itraconazole Onmel, Sporanox , ketoconazole Nizoral , and voriconazole Vfend ; benzodiazepines such as alprazolam Xanax , diazepam Diastat, Valium , estazolam, flurazepam, lorazepam Ativan , and triazolam Halcion ; carbamazepine Carbatrol, Epitol, Equetro, Tegretol, Teril ; erythromycin Erytab, Erythrocin ; certain medications for human immunodeficiency virus HIV including indinavir Crixivan , nelfinavir Viracept , and ritonavir Norvir, in Kaletra ; medications for mental illness, nausea, or pain; muscle relaxants; phenytoin Dilantin, Phenytek ; quinidine in Nuedexta ; rifampin Rifadin, Rimactane, in Rifamate ; sedatives; sleeping pills; or tranquilizers.
Your doctor may need to change the dosages of your medications and will monitor you carefully. If you take tramadol with any of these medications and you develop any of the following symptoms, call your doctor immediately or seek emergency medical care: unusual dizziness, lightheadedness, extreme sleepiness, slowed or difficult breathing, or unresponsiveness.
Be sure that your caregiver or family members know which symptoms may be serious so they can call the doctor or emergency medical care if you are unable to seek treatment on your own.
Drinking alcohol, taking prescription or nonprescription medications that contain alcohol, or using street drugs during your treatment with tramadol increases the risk that you will experience these serious, life-threatening side effects. Do not drink alcohol, take prescription or nonprescription medications that contain alcohol, or use street drugs during your treatment. Tell your doctor if you are pregnant or plan to become pregnant.
If you take tramadol regularly during your pregnancy, your baby may experience life-threatening withdrawal symptoms after birth. Tell your baby's doctor right away if your baby experiences any of the following symptoms: irritability, hyperactivity, abnormal sleep, high-pitched cry, uncontrollable shaking of a part of the body, vomiting, diarrhea, or failure to gain weight. If you are taking the tramadol extended-release tablet or capsule, swallow them whole; do not chew, break, divide, crush, or dissolve them.
Swallow each tablet right after you put it in your mouth. If you swallow broken, chewed, crushed, or dissolved extended-release preparations, you may receive too much tramadol at once instead and this may cause serious problems, including overdose and death. Do not allow anyone else to take your medication. Tramadol may harm or cause death to other people who take your medication, especially children.
Your doctor or pharmacist will give you the manufacturer's patient information sheet Medication Guide when you begin treatment with tramadol and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions.
Tramadol is used to relieve moderate to moderately severe pain. Tramadol extended-release tablets and capsules are only used by people who are expected to need medication to relieve pain around-the-clock.
Tramadol is in a class of medications called opiate narcotic analgesics. It works by changing the way the brain and nervous system respond to pain. Tramadol comes as a tablet, a solution liquid , an extended-release long-acting tablet, and an extended-release long-acting capsule to take by mouth. The regular tablet and solution are taken usually with or without food every 4 to 6 hours as needed.
The extended-release tablet and extended-release capsule should be taken once a day. Take the extended-release tablet and the extended-release capsule at about the same time of day every day.
If you are taking the extended-release capsule, you may take it with or without food. If you are taking the extended-release tablet, you should either always take it with food or always take it without food. Do not take more medication as a single dose or take more doses per day than prescribed by your doctor. Taking more tramadol than prescribed by your doctor or in a way that is not recommended may cause serious side effects or death.
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